Over the last few years, there has been an increase in information on research peptides and peptide research on the net. Many people till date have never heard about research peptides, if you also don’t know, than type “research peptides” on Google search engine and you will find several in a minute!
What are peptides and Research peptides?
A peptide is a chain of amino acids that are linked to one another by peptide bonds. A peptide bond is the covalent chemical bond formed when the one amino acids’ carboxyl group reacts with the amino group of another. Research peptides are a chemical formula in the physical state which are available for research purpose.
There are several types and classes of peptides, on which the research focus that include ribosomal peptides, milk peptides, peptide fragments, and nonribosomal peptides.
There are several laboratories that synthesis peptides using MS (Mass Spectrometry) and HPLC (High-performance liquid chromatography). MS and HPLC help check the mass content and purity content of the sample. HPLC is usually performed many times during peptide synthesis while MS is used for result analysis.
By completing extensive research, scientists were able to synthesize various peptides, each more unique from the other. Research peptides such as Melanotan, Ipamorelin, a pentapeptide that display high gH releasing potency and efficacy in vivo and in vitro, Sermorelin, which were studied in clinical trials to test whether or not they could be used on humans.
Here I will focus on Sermorelin, 29 amino acid peptide of human growth hormone-releasing hormone (GHRH), which has been discovered as an effective way to fight the side effects of cellular degradation. It does this by triggering the brain to release an increased amount of growth hormone. Sermorelin Acetate GHRH has been approved for increasing growth hormone levels.
Research peptides have been discovered and supplied by several biotechnology firms in different physical forms such as powder, liquid, etc. Sermorelin is a GHRH analogue, which has molecular formula C149H246N44O42S and a molecular mass of 3357.96. It has been recognized as the shortest fully functional fragment of gH releasing hormone. Read related information at https://www.pharmacist.com/talon-compounding-pharmacy-recalls-hcg-and-sermorelin
What are the meaning of peptide purity and the role played by it in research?
Peptide purity usually ranges from over 70% to 99 %. This purity level is selected by the firm that requests custom peptide synthesis and purity varies based on the required use of the peptides. Peptides with a purity more than 70% are always used to test antibodies, while peptides with purity level over 85% are normally utilized for biological activity and enzymology studies. Peptides with purity over 95% are best for the quantitative analysis. Peptides with purity level more than 98% are excellent for non-commercial research.